Clinical Study

Study To Evaluate The Effect Of Isotretinoin On Immune Activation In Hiv With Lower Cd4+ T Cell Counts On Suppressive Antiretroviral Treatment

Posted Date: May 18, 2016

  • Investigator: Carl Fichtenbaum
  • Specialties: AIDS-HIV, Infectious Diseases
  • Type of Study: Drug

This study is being done to find out if taking a high dose of isotretinoin is safe and well-tolerated in people infected with HIV who are on anti-HIV medication. Isotretinoin is a drug that is approved to treat severe acne. Your immune system helps your body fight infections. We know that HIV infection damages the immune system. The study aims to find out whether isotretinoin can help improve the immune system by repairing some of the damage that HIV causes. When your immune system is not working well, you may be more prone to diseases that are common in aging, like heart disease, weaker bones, and kidney disease.


You Are Being Asked To Take Part In This Research Study Because You Are Age 18 To 80 Years Of Age, A Man Or Post-Menopausal Woman, Are Infected With Hiv (The Virus That Causes Aids), And You Have Been Taking Anti-Hiv Treatment That Has Been Controlling Your Infection For At Least The Past 1 Year.


Aids, Hiv, Immune Activation, Inflammation, Isotretinoin

For More Information:

Tammy Miller