Clinical Study

Transbronchial Cryobiopsy In Diagnosing Interstitial Lung Disease: How Many Biopsies Are Needed?

Posted Date: Nov 18, 2015

  • Investigator: Sadia Benzaquen
  • Specialties: Thoracic Surgery, Pulmonary Diseases, Rheumatology
  • Type of Study: Device

We are doing this study to get more information on this type of lung biopsy. Our hospital does more cryobiopsies than anyone else in the United States. This type of biopsy has become standard in our practice. We want to answer two questions: 1) How many biopsies are necessary? 2) Is there a difference between a small biopsy tool and a large biopsy tool? So far we have been getting 5 biopsy pieces to make sure that we get enough material, however we do not know if getting fewer biopsies (3) would be just as good. We also don’t know if using a small biopsy tool is different from using a large biopsy tool. So far we have used both interchangeably. From our experience we believe that both tools are probably the same, but we want to compare them to know for sure. The device we use to take these biopsies is called ERBEKRYO, and uses liquid nitrogen to freeze the tip of a biopsy tool. We put the tool into the lung and freeze a small piece of lung tissue. The lung tissue around the tip of the tool gets stuck and comes out easily. That’s how we get pieces of lung tissue to analyze under the microscope.


You Are Being Asked To Take Part In This Research Study Because You Are Over 18 Years Old And You Have Been Diagnosed With A Lung Condition That Causes Scarring. Your Doctor Would Like For You To Have A Biopsy Procedure To Help Determine What Kind Of Lung Scarring You Have. Within This Category Of “Lung Scarring” There Are Many Different Diseases That Have Different Treatments. It’S Important To Know Which Kind You Have To Make Decisions. You Will Be Able To Have This Procedure Done Even If You Do Not Sign Up For The Study.


Pulmonary Fibrosis, Interstitial Lung Disease, Lung Biopsy, Cryobiopsy

For More Information:

Rick Balestra

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