Clinical Research Experience

The University of Cincinnati (UC) has a rich history in medical discovery and innovation. UC is accredited to conduct clinical research by the Association for the Accreditation of Human Research Protection Programs (AAHRPP). Researchers routinely conduct industry, investigator-initiated and National Institutes of Health (NIH) sponsored clinical trials (phase I-IV) in nearly all therapeutic areas, conforming to regulatory requirements in an efficient and cost-effective manner.

Through our large network of providers and patient databases, we have access to disease-specific subject populations.

Researchers are supported by Good Clinical Practice (GCP) trained coordinators and have access to a variety of services that aid in the clinical research process, including:

acheivements

  • Local and central Institutional Review Boards (IRBs)
  • UC Health Office of Clinical Research
  • Investigational pharmacy
  • Comprehensive laboratory services
  • Marketing and participant recruitment support
  • Education and training

Achievements

The University of Cincinnati (UC) is classified as a “very high” research university by the Carnegie Commission and is consistently ranked as one of America’s top public research universities for expenditures according to the National Science Foundation. Research performed under the umbrella of the UC Academic Health Center plays an important role in these efforts, contributing more than 70 percent annually to the university’s total research enterprise.

UC has seen a number of historical achievements, including the definitive study of the health effects of lead in children and the development of the popular antihistamine Benadryl. More recently, UC researchers were responsible for the development of a treatment to reduce brain damage in stroke patients. Through its affiliation with Cincinnati Children’s Hospital Medical Center, the university also played an important role in the development of the first live, attenuated polio vaccine and the first functional heart-lung machine.

The UC Cancer Institute is the only center within 100 miles of Cincinnati to offer an early stage drug trial program. This program focuses on phase-I “first-in-human” clinical trials, offering the most up-to-date care concepts to patients who do not respond to standard treatments.

UC and its affiliates have been rewarded by the NIH for their sustained excellence in clinical research with an institutional Clinical and Translational Science Award (CTSA). The CTSA program supports a national consortium of academic medical institutions working together to transform the way biomedical research is conducted. Locally, the grant has supported the efforts of the Center for Clinical and Translational Science and Training (CCTST) to speed the translation of laboratory discoveries into treatments for patients, to engage communities in clinical research efforts, and to train a new generation of clinical and translational researchers.

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  • Research in the News

    Trial and Error: Researchers Publish Findings From First UC Phase I Trial

    UC researchers published a study, the first from the Phase I program whichbegan in 2010, which unfortunately didn't have great outcomes but that taughtthem a lot.