Clinical Study

Stroke Hyperglycemia Insulin Network Effort (Shine) Trial

Posted Date: Oct 11, 2017

  • Investigator: Opeolu Adeoye
  • Co-Investigator: Emily Werff
  • Specialties: Diabetes, Emergency Medicine, Stroke
  • Type of Study: Drug

The purpose of this research study is to find out if treating high blood sugar in stroke patients with IV insulin shows better recoveries than the current standard care for treating high blood sugar. Laboratory and human studies have shown that high blood sugar levels during a stroke can be associated with more damage to the brain than normal blood sugar levels. Blood sugar levels can be lowered with a hormone called insulin, which can either be given as a shot under your skin (subcutaneously) or into a vein in your arm through a tube called an IV. IV insulin for blood sugar control has been shown to be a safe treatment in previous studies of acute stroke patients. The next step is to learn if this treatment can improve recovery after stroke. Insulin is approved by the FDA for use in the treatment of high blood sugar.


You Are Being Asked To Take Part In This Research Study Because: -You Are 18 Years Or Older -You Have Recently Had A Stroke Caused By A Blood Clot In Your Brain -You Have Either A History Of Type 2 Diabetes And A Blood Sugar Level Above 110 Milligrams/Dl. Or -No History Of Type 2 Diabetes And A Blood Sugar Level At Or Above 150 Milligrams/Dl.ª


Emergency Medicine, Stoke, Diabetes, Null, Null

For More Information:

Irene Ewing
(513) 558-3450

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