Clinical Study

A Multicenter Phase 1/2B Study Of The Bruton’S Tyrosine Kinase Inhibitor, Ibrutinib (Pci-32765), In Combination With Carfilzomib (Kyprolis™) In Subjects With Relapsed Or Relapsed And Refractory Multiple Myeloma

Posted Date: Aug 2, 2017

  • Investigator: Saulius Girnius
  • Co-Investigator: Bridget Kinne
  • Specialties: Hematology/Oncology, Oncology, Cancer
  • Type of Study: Drug

The study drug Ibrutinib (PCI-32765 or IMBRUVICA®) is a type of drug called a kinase inhibitor. Kinases are proteins that help cells live and grow. The specific kinase blocked by ibrutinib is believed to help blood cancer cells live and grow. By inhibiting the activity of this specific kinase, it is possible that ibrutinib may kill the cancer cells or stop them from growing. Ibrutinib has been approved by the U.S FDA for the treatment of mantle cell lymphoma, chronic lymphocytic leukemia and CLL in patients with 17p deletion


To Be Eligible For This Study, Patients Must Have Multiple Myeloma


Pcyc-1119-Ca, Phase I, Cancer, Multiple Myeloma, Hematology

For More Information:

Uc Cancer Institute

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